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Tumor Necrosis Factor-Alpha and the ERK Pathway Drive Chemerin Expression in Response to Hypoxia in Cultured Human Coronary Artery Endothelial Cells

BACKGROUND: Chemerin, a novel adipokine, plays a role in the inflammation status of vascular endothelial cells. Hypoxia causes endothelial-cell proliferation, migration, and angiogenesis. This study was aimed at evaluating the protein and mRNA expression of chemerin after exposure of human coronary...

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Detalles Bibliográficos
Autores principales: Chua, Su-Kiat, Shyu, Kou-Gi, Lin, Yuh-Feng, Lo, Huey-Ming, Wang, Bao-Wei, Chang, Hang, Lien, Li-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085022/
https://www.ncbi.nlm.nih.gov/pubmed/27792771
http://dx.doi.org/10.1371/journal.pone.0165613