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Premature Discontinuation of Prospective Clinical Studies Approved by a Research Ethics Committee – A Comparison of Randomised and Non-Randomised Studies

BACKGROUND: Premature discontinuation of clinical studies affects about 25% of randomised controlled trials (RCTs) which raises concerns about waste of scarce resources for research. The risk of discontinuation of non-randomised prospective studies (NPSs) is yet unclear. OBJECTIVES: To compare the p...

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Detalles Bibliográficos
Autores principales: Blümle, Anette, Schandelmaier, Stefan, Oeller, Patrick, Kasenda, Benjamin, Briel, Matthias, von Elm, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085068/
https://www.ncbi.nlm.nih.gov/pubmed/27792749
http://dx.doi.org/10.1371/journal.pone.0165605