Cargando…

Pdlim7 Regulates Arf6-Dependent Actin Dynamics and Is Required for Platelet-Mediated Thrombosis in Mice

Upon vessel injury, platelets become activated and rapidly reorganize their actin cytoskeleton to adhere to the site of endothelial damage, triggering the formation of a fibrin-rich plug to prevent further blood loss. Inactivation of Pdlim7 provides the new perspective that regulation of actin cytos...

Descripción completa

Detalles Bibliográficos
Autores principales: Urban, Alexander E., Quick, Erin O., Miller, Kaylie P., Krcmery, Jennifer, Simon, Hans-Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085081/
https://www.ncbi.nlm.nih.gov/pubmed/27792740
http://dx.doi.org/10.1371/journal.pone.0164042