A Decoy Peptide Targeted to Protein Phosphatase 1 Attenuates Degradation of SERCA2a in Vascular Smooth Muscle Cells

Neointimal growth in the injured vasculature is largely facilitated by the proliferation of vascular smooth muscle cells (VSMC), which associates with reduced sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA2a) activity. The gene transfer-mediated restoration of the SERCA2a level thus attenuates neo...

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Detalles Bibliográficos
Autores principales: Jang, Seung Pil, Oh, Jae Gyun, Kang, Dong Hoon, Kang, Ju Young, Kang, Sang Won, Hajjar, Roger J., Park, Woo Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085086/
https://www.ncbi.nlm.nih.gov/pubmed/27792751
http://dx.doi.org/10.1371/journal.pone.0165569

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