Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype

Pulmonary research requires models that represent the physiology of alveolar epithelium but concerns with reproducibility, consistency and the technical and ethical challenges of using primary or stem cells has resulted in widespread use of continuous cancer or other immortalized cell lines. The A54...

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Detalles Bibliográficos
Autores principales: Cooper, James Ross, Abdullatif, Muhammad Bilal, Burnett, Edward C., Kempsell, Karen E., Conforti, Franco, Tolley, Howard, Collins, Jane E., Davies, Donna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085087/
https://www.ncbi.nlm.nih.gov/pubmed/27792742
http://dx.doi.org/10.1371/journal.pone.0164438

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