High-Accuracy HLA Type Inference from Whole-Genome Sequencing Data Using Population Reference Graphs

Genetic variation at the Human Leucocyte Antigen (HLA) genes is associated with many autoimmune and infectious disease phenotypes, is an important element of the immunological distinction between self and non-self, and shapes immune epitope repertoires. Determining the allelic state of the HLA genes...

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Detalles Bibliográficos
Autores principales: Dilthey, Alexander T., Gourraud, Pierre-Antoine, Mentzer, Alexander J., Cereb, Nezih, Iqbal, Zamin, McVean, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085092/
https://www.ncbi.nlm.nih.gov/pubmed/27792722
http://dx.doi.org/10.1371/journal.pcbi.1005151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085092/
https://www.ncbi.nlm.nih.gov/pubmed/27792722
http://dx.doi.org/10.1371/journal.pcbi.1005151

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