Heritable DNA Methylation in CD4(+) Cells among Complex Families Displays Genetic and Non-Genetic Effects

DNA methylation at CpG sites is both heritable and influenced by environment, but the relative contributions of each to DNA methylation levels are unclear. We conducted a heritability analysis of CpG methylation in human CD4(+) cells across 975 individuals from 163 families in the Genetics of Lipid-...

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Detalles Bibliográficos
Autores principales: Day, Kenneth, Waite, Lindsay L., Alonso, Arnald, Irvin, Marguerite R., Zhi, Degui, Thibeault, Krista S., Aslibekyan, Stella, Hidalgo, Bertha, Borecki, Ingrid B., Ordovas, Jose M., Arnett, Donna K., Tiwari, Hemant K., Absher, Devin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085095/
https://www.ncbi.nlm.nih.gov/pubmed/27792787
http://dx.doi.org/10.1371/journal.pone.0165488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085095/
https://www.ncbi.nlm.nih.gov/pubmed/27792787
http://dx.doi.org/10.1371/journal.pone.0165488

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