Cargando…
AMPK-dependent and independent effects of AICAR and compound C on T-cell responses
As a master metabolic sensor, AMP-activated protein kinase (AMPK) is involved in different fundamental cellular processes. Regulation of AMPK activity either by agonists (e.g., AICAR) or by antagonists (e.g., Compound C) has been widely employed to study the physiological functions of AMPK. However,...
Autores principales: | Rao, Enyu, Zhang, Yuwen, Li, Qiang, Hao, Jiaqing, Egilmez, Nejat K., Suttles, Jill, Li, Bing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085118/ https://www.ncbi.nlm.nih.gov/pubmed/27177226 http://dx.doi.org/10.18632/oncotarget.9277 |
Ejemplares similares
-
Deficiency of AMPK in CD8(+) T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death
por: Rao, Enyu, et al.
Publicado: (2015) -
AMPK-independent inhibition of human macrophage ER stress response by AICAR
por: Boß, Marcel, et al.
Publicado: (2016) -
Targeting epidermal fatty acid binding protein for treatment of experimental autoimmune encephalomyelitis
por: Rao, Enyu, et al.
Publicado: (2015) -
AICAr, a Widely Used AMPK Activator with Important AMPK-Independent Effects: A Systematic Review
por: Višnjić, Dora, et al.
Publicado: (2021) -
AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia
por: Leclerc, Gilles M, et al.
Publicado: (2010)