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Rheb may complex with RASSF1A to coordinate Hippo and TOR signaling
The TOR pathway is a vital component of cellular homeostasis that controls the synthesis of proteins, nucleic acids and lipids. Its core is the TOR kinase. Activation of the TOR pathway suppresses autophagy, which plays a vital but complex role in tumorigenesis. The TOR pathway is regulated by activ...
Autores principales: | Nelson, Nicholas, Clark, Geoffrey J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085121/ https://www.ncbi.nlm.nih.gov/pubmed/27034171 http://dx.doi.org/10.18632/oncotarget.8447 |
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