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Lapatinib-loaded human serum albumin nanoparticles for the prevention and treatment of triple-negative breast cancer metastasis to the brain

Brain metastasis from triple-negative breast cancer (TNBC) has continued to lack effective clinical treatments until present. However, the feature of epidermal growth factor receptor (EGFR) frequently overexpressed in TNBC offers the opportunity to employ lapatinib, a dual-tyrosine kinase inhibitor...

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Detalles Bibliográficos
Autores principales: Wan, Xu, Zheng, Xiaoyao, Pang, Xiaoyin, Pang, Zhiqing, Zhao, Jingjing, Zhang, Zheming, Jiang, Tao, Xu, Wei, Zhang, Qizhi, Jiang, Xinguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085136/
https://www.ncbi.nlm.nih.gov/pubmed/27086917
http://dx.doi.org/10.18632/oncotarget.8697