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HIF-1-alpha links mitochondrial perturbation to the dynamic acquisition of breast cancer tumorigenicity

Up-regulation of hypoxia-inducible factor-1α (HIF-1α), even in normoxia, is a common feature of solid malignancies. However, the mechanisms of increased HIF-1α abundance, and its role in regulating breast cancer plasticity are not fully understood. We have previously demonstrated that dimethyl-2-ket...

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Detalles Bibliográficos
Autores principales: Kuo, Ching-Ying, Cheng, Chun-Ting, Hou, Peifeng, Lin, Yi-Pei, Ma, Huimin, Chung, Yiyin, Chi, Kevin, Chen, Yuan, Li, Wei, Kung, Hsing-Jien, Ann, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085137/
https://www.ncbi.nlm.nih.gov/pubmed/27058900
http://dx.doi.org/10.18632/oncotarget.8570

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