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Asparaginyl endopeptidase promotes the invasion and metastasis of gastric cancer through modulating epithelial-to-mesenchymal transition
Asparaginyl endopeptidase (AEP) is a lysosomal protease often overexpressed in gastric cancer. AEP was expressed higher in peritoneal metastatic loci than in primary gastric cancer. Then we overexpressed AEP or knocked it down with a lentiviral vector in gastric cancer cell lines and detected the ce...
Autores principales: | Cui, Yuehong, Wang, Yan, Li, Hong, Li, Qian, Yu, Yiyi, Xu, Xiaojing, Xu, Bei, Liu, Tianshu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085161/ https://www.ncbi.nlm.nih.gov/pubmed/27102302 http://dx.doi.org/10.18632/oncotarget.8879 |
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