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Metformin blocks progression of obesity-activated thyroid cancer in a mouse model

Compelling epidemiologic evidence indicates that obesity is associated with a high risk of human malignancies, including thyroid cancer. We previously demonstrated that a high fat diet (HFD) effectively induces the obese phenotype in a mouse model of aggressive follicular thyroid cancer (Thrb(PV/PV)...

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Detalles Bibliográficos
Autores principales: Park, Jeongwon, Kim, Won Gu, Zhao, Li, Enomoto, Keisuke, Willingham, Mark, Cheng, Sheue-Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085193/
https://www.ncbi.nlm.nih.gov/pubmed/27145454
http://dx.doi.org/10.18632/oncotarget.8989