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BIS-mediated STAT3 stabilization regulates glioblastoma stem cell-like phenotypes

Glioblastoma stem cells (GSCs) are a subpopulation of highly tumorigenic and stem-like cells that are responsible for resistance to conventional therapy. Bcl-2-intreacting cell death suppressor (BIS; also known as BAG3) is an anti-apoptotic protein that is highly expressed in human cancers with vari...

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Detalles Bibliográficos
Autores principales: Im, Chang-Nim, Yun, Hye Hyeon, Song, Byunghoo, Youn, Dong-Ye, Cui, Mei Nu, Kim, Hong Sug, Park, Gyeong Sin, Lee, Jeong-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085209/
https://www.ncbi.nlm.nih.gov/pubmed/27145367
http://dx.doi.org/10.18632/oncotarget.9039