Cargando…

Solid tumors provide niche-specific conditions that lead to preferential growth of Salmonella

Therapeutic attenuated strains of Salmonella Typhimurium target and eradicate tumors in mouse models. However, the mechanism of S. Typhimurium for tumor targeting is still poorly understood. We performed a high-throughput screening of single-gene deletion mutants of S. Typhimurium in an orthotopic,...

Descripción completa

Detalles Bibliográficos
Autores principales: Silva-Valenzuela, Cecilia A., Desai, Prerak T., Molina-Quiroz, Roberto C., Pezoa, David, Zhang, Yong, Porwollik, Steffen, Zhao, Ming, Hoffman, Robert M., Contreras, Inés, Santiviago, Carlos A., McClelland, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085218/
https://www.ncbi.nlm.nih.gov/pubmed/27145267
http://dx.doi.org/10.18632/oncotarget.9071