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miR-592/WSB1/HIF-1α axis inhibits glycolytic metabolism to decrease hepatocellular carcinoma growth
Hepatocellular carcinoma (HCC) cells rapidly switch their energy source from oxidative phosphorylation to glycolytic metabolism in order to efficiently proliferate. However, the molecular mechanisms responsible for this switch remain unclear. In this study, we found that miR-592 was frequently downr...
Autores principales: | Jia, Yan-Yan, Zhao, Jin-Yi, Li, Bing-Ling, Gao, Kai, Song, Ying, Liu, Mei-You, Yang, Xiao-Juan, Xue, Yan, Wen, Ai-Dong, Shi, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085226/ https://www.ncbi.nlm.nih.gov/pubmed/27153552 http://dx.doi.org/10.18632/oncotarget.9135 |
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