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miR-592/WSB1/HIF-1α axis inhibits glycolytic metabolism to decrease hepatocellular carcinoma growth

Hepatocellular carcinoma (HCC) cells rapidly switch their energy source from oxidative phosphorylation to glycolytic metabolism in order to efficiently proliferate. However, the molecular mechanisms responsible for this switch remain unclear. In this study, we found that miR-592 was frequently downr...

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Detalles Bibliográficos
Autores principales: Jia, Yan-Yan, Zhao, Jin-Yi, Li, Bing-Ling, Gao, Kai, Song, Ying, Liu, Mei-You, Yang, Xiao-Juan, Xue, Yan, Wen, Ai-Dong, Shi, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085226/
https://www.ncbi.nlm.nih.gov/pubmed/27153552
http://dx.doi.org/10.18632/oncotarget.9135

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