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STING-Licensed Macrophages Prime Type I IFN Production by Plasmacytoid Dendritic Cells in the Bone Marrow during Severe Plasmodium yoelii Malaria
Malaria remains a global health burden causing significant morbidity, yet the mechanisms underlying disease outcomes and protection are poorly understood. Herein, we analyzed the peripheral blood of a unique cohort of Malawian children with severe malaria, and performed a comprehensive overview of b...
Autores principales: | Spaulding, Emily, Fooksman, David, Moore, Jamie M., Saidi, Alex, Feintuch, Catherine M., Reizis, Boris, Chorro, Laurent, Daily, Johanna, Lauvau, Grégoire |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085251/ https://www.ncbi.nlm.nih.gov/pubmed/27792766 http://dx.doi.org/10.1371/journal.ppat.1005975 |
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