Genetic Evidence for Elevated Pathogenicity of Mitochondrial DNA Heteroplasmy in Autism Spectrum Disorder

Increasing clinical and biochemical evidence implicate mitochondrial dysfunction in the pathophysiology of Autism Spectrum Disorder (ASD), but little is known about the biological basis for this connection. A possible cause of ASD is the genetic variation in the mitochondrial DNA (mtDNA) sequence, w...

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Detalles Bibliográficos
Autores principales: Wang, Yiqin, Picard, Martin, Gu, Zhenglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085253/
https://www.ncbi.nlm.nih.gov/pubmed/27792786
http://dx.doi.org/10.1371/journal.pgen.1006391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085253/
https://www.ncbi.nlm.nih.gov/pubmed/27792786
http://dx.doi.org/10.1371/journal.pgen.1006391

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