Cargando…
Structure of NS3 helicase from Zika virus
The Zika virus has emerged as a pathogen of major health concern. We present a high-resolution (1.62Å) crystal structure of the RNA helicase from the French Polynesia strain. The structure is similar to that of the RNA helicase from Dengue virus, with variability in the conformations of loops typica...
Autores principales: | Jain, Rinku, Coloma, Javier, García-Sastre, Adolfo, Aggarwal, Aneel K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085289/ https://www.ncbi.nlm.nih.gov/pubmed/27399257 http://dx.doi.org/10.1038/nsmb.3258 |
Ejemplares similares
-
Structures of NS5 Methyltransferase from Zika Virus
por: Coloma, Javier, et al.
Publicado: (2016) -
Development of a S-adenosylmethionine analog that intrudes the RNA-cap binding site of Zika methyltransferase
por: Jain, Rinku, et al.
Publicado: (2017) -
Molecular docking and simulation of Zika virus NS3 helicase
por: Badshah, Syed Lal, et al.
Publicado: (2019) -
Zika virus NS3 is a canonical RNA helicase stimulated by NS5 RNA polymerase
por: Xu, Shan, et al.
Publicado: (2019) -
Mechanistic Insights into Zika Virus NS3 Helicase
Inhibition by Epigallocatechin-3-Gallate
por: Kumar, Deepak, et al.
Publicado: (2020)