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Quantum dot-based immunofluorescent imaging and quantitative detection of TOP2A and prognostic value in triple-negative breast cancer

BACKGROUND: Topoisomerase 2 alpha (TOP2A) is a key enzyme in DNA replication and a target of various cytotoxic agents including anthracyclines. Previous studies evaluating the predictive and prognostic values of TOP2A in breast cancer are contradictory, likely secondary to the use of both different...

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Detalles Bibliográficos
Autores principales: Zheng, Hongmei, Li, Xiang, Chen, Chuang, Chen, Jian, Sun, Jinzhong, Sun, Si, Jin, Liting, Li, Juanjuan, Sun, Shengrong, Wu, Xinhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085300/
https://www.ncbi.nlm.nih.gov/pubmed/27799773
http://dx.doi.org/10.2147/IJN.S111594