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Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants

Viruses manipulate host factors to enhance their replication and evade cellular restriction. We used multiplex tandem mass tag (TMT)-based whole cell proteomics to perform a comprehensive time course analysis of >6500 viral and cellular proteins during HIV infection. To enable specific functional...

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Detalles Bibliográficos
Autores principales: Greenwood, Edward JD, Matheson, Nicholas J, Wals, Kim, van den Boomen, Dick JH, Antrobus, Robin, Williamson, James C, Lehner, Paul J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085607/
https://www.ncbi.nlm.nih.gov/pubmed/27690223
http://dx.doi.org/10.7554/eLife.18296