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Morphine Protects Spinal Cord Astrocytes from Glutamate-Induced Apoptosis via Reducing Endoplasmic Reticulum Stress

Glutamate is not only a neurotransmitter but also an important neurotoxin in central nervous system (CNS). Chronic elevation of glutamate induces both neuronal and glial cell apoptosis. However, its effect on astrocytes is complex and still remains unclear. In this study, we investigated whether mor...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Wang, Chendan, Ren, Jianbo, Guo, Xiangjie, Yun, Keming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085616/
https://www.ncbi.nlm.nih.gov/pubmed/27783050
http://dx.doi.org/10.3390/ijms17101523