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Recent Advances in Understanding Amino Acid Sensing Mechanisms that Regulate mTORC1

The mammalian target of rapamycin (mTOR) is the central regulator of mammalian cell growth, and is essential for the formation of two structurally and functionally distinct complexes: mTORC1 and mTORC2. mTORC1 can sense multiple cues such as nutrients, energy status, growth factors and hormones to c...

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Detalles Bibliográficos
Autores principales: Zheng, Liufeng, Zhang, Wei, Zhou, Yuanfei, Li, Fengna, Wei, Hongkui, Peng, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085669/
https://www.ncbi.nlm.nih.gov/pubmed/27690010
http://dx.doi.org/10.3390/ijms17101636