Homeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the Epigenome

Homeodomain-interacting protein kinase 2 (HIPK2) is a serine/threonine kinase that phosphorylates and activates the apoptotic program through interaction with diverse downstream targets including tumor suppressor p53. HIPK2 is activated by genotoxic stimuli and modulates cell fate following DNA dama...

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Detalles Bibliográficos
Autores principales: Kuwano, Yuki, Nishida, Kensei, Akaike, Yoko, Kurokawa, Ken, Nishikawa, Tatsuya, Masuda, Kiyoshi, Rokutan, Kazuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085671/
https://www.ncbi.nlm.nih.gov/pubmed/27689990
http://dx.doi.org/10.3390/ijms17101638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085671/
https://www.ncbi.nlm.nih.gov/pubmed/27689990
http://dx.doi.org/10.3390/ijms17101638

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