GSPE Inhibits HMGB1 Release, Attenuating Renal IR-Induced Acute Renal Injury and Chronic Renal Fibrosis

Grape seed proanthocyanindin extract (GSPE) is a polyphenolic bioflavonoid derived from grape seeds and has been widely studied for its potent antioxidant, anti-inflammatory and antitumor activities. HMGB1 is a newly discovered danger-associated molecular pattern (DAMP) that has potent proinflammato...

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Detalles Bibliográficos
Autores principales: Zhan, Juan, Wang, Kun, Zhang, Conghui, Zhang, Chunxiu, Li, Yueqiang, Zhang, Ying, Chang, Xiaoyan, Zhou, Qiaodan, Yao, Ying, Liu, Yanyan, Xu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085680/
https://www.ncbi.nlm.nih.gov/pubmed/27690015
http://dx.doi.org/10.3390/ijms17101647

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