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Overexpression of microRNA-21 strengthens stem cell-like characteristics in a hepatocellular carcinoma cell line

BACKGROUND: Liver cancer stem cells (LCSCs) have been shown to express higher levels of microRNA-21 (miR-21). Here, we examine the possible contributions of miR-21 to the phenotype of LCSCs in culture and in xenograft tumors in nude mice. METHODS: The hepatocellular carcinoma cell line MHCC-97H was...

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Detalles Bibliográficos
Autores principales:	Jiang, Jinghang, Yang, Peipei, Guo, Zhe, Yang, Rirong, Yang, Haojie, Yang, Fuquan, Li, Lequn, Xiang, Bangde
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086074/ https://www.ncbi.nlm.nih.gov/pubmed/27793160 http://dx.doi.org/10.1186/s12957-016-1028-9

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