Common variants at PVT1, ATG13–AMBRA1, AHI1 and CLEC16A are associated with selective IgA deficiency

Selective immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in Europeans. Our GWAS meta-analysis of 1,635 IgAD patients and 4,852 controls identified four new significant (P < 5x10(−8)) loci and association with a rare IFIH1 variant (Ile923Val). Peak novel variants (P...

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Detalles Bibliográficos
Autores principales: Bronson, Paola G., Chang, Diana, Bhangale, Tushar, Seldin, Michael F., Ortmann, Ward, Ferreira, Ricardo C., Urcelay, Elena, Pereira, Luis Fernández, Martin, Javier, Plebani, Alessandro, Lougaris, Vassilios, Friman, Vanda, Freiberger, Tomáš, Litzman, Jiri, Thon, Vojtech, Pan-Hammarström, Qiang, Hammarström, Lennart, Graham, Robert R., Behrens, Timothy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086090/
https://www.ncbi.nlm.nih.gov/pubmed/27723758
http://dx.doi.org/10.1038/ng.3675

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