Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation

Carbapenem-resistant Klebsiella pneumoniae (CR-KP) infections in solid organ transplant recipients are associated with high morbidity and mortality. We report a case of a fatal donor-derived CR-KP infection in a combined kidney-pancreas transplant. Given the short interval of time between donor hosp...

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Autores principales: Varotti, Giovanni, Dodi, Ferdinando, Marchese, Anna, Terulla, Alessia, Bertocchi, Massimo, Fontana, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086363/
https://www.ncbi.nlm.nih.gov/pubmed/27822401
http://dx.doi.org/10.1155/2016/7920951
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author Varotti, Giovanni
Dodi, Ferdinando
Marchese, Anna
Terulla, Alessia
Bertocchi, Massimo
Fontana, Iris
author_facet Varotti, Giovanni
Dodi, Ferdinando
Marchese, Anna
Terulla, Alessia
Bertocchi, Massimo
Fontana, Iris
author_sort Varotti, Giovanni
collection PubMed
description Carbapenem-resistant Klebsiella pneumoniae (CR-KP) infections in solid organ transplant recipients are associated with high morbidity and mortality. We report a case of a fatal donor-derived CR-KP infection in a combined kidney-pancreas transplant. Given the short interval of time between donor hospitalization and organ procurement, information concerning the donor CR-KP positivity arrived only 72 hours after transplant. Based on this experience, we believe that knowledge of the donor's CR-KP status should be mandatory before procurement and, if positive, pancreas donation should be contraindicated.
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spelling pubmed-50863632016-11-07 Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation Varotti, Giovanni Dodi, Ferdinando Marchese, Anna Terulla, Alessia Bertocchi, Massimo Fontana, Iris Case Rep Transplant Case Report Carbapenem-resistant Klebsiella pneumoniae (CR-KP) infections in solid organ transplant recipients are associated with high morbidity and mortality. We report a case of a fatal donor-derived CR-KP infection in a combined kidney-pancreas transplant. Given the short interval of time between donor hospitalization and organ procurement, information concerning the donor CR-KP positivity arrived only 72 hours after transplant. Based on this experience, we believe that knowledge of the donor's CR-KP status should be mandatory before procurement and, if positive, pancreas donation should be contraindicated. Hindawi Publishing Corporation 2016 2016-10-16 /pmc/articles/PMC5086363/ /pubmed/27822401 http://dx.doi.org/10.1155/2016/7920951 Text en Copyright © 2016 Giovanni Varotti et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Varotti, Giovanni
Dodi, Ferdinando
Marchese, Anna
Terulla, Alessia
Bertocchi, Massimo
Fontana, Iris
Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation
title Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation
title_full Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation
title_fullStr Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation
title_full_unstemmed Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation
title_short Fatal Donor-Derived Carbapenem-Resistant Klebsiella pneumoniae Infection in a Combined Kidney-Pancreas Transplantation
title_sort fatal donor-derived carbapenem-resistant klebsiella pneumoniae infection in a combined kidney-pancreas transplantation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086363/
https://www.ncbi.nlm.nih.gov/pubmed/27822401
http://dx.doi.org/10.1155/2016/7920951
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