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Development of Auto Antigen-specific Regulatory T Cells for Diabetes Immunotherapy
CD4(+) regulatory T cells (Tregs) are essential for normal immune surveillance, and their dysfunction can lead to the development of autoimmune diseases, such as type-1 diabetes (T1D). T1D is a T cell-mediated autoimmune disease characterized by islet β cell destruction, hypoinsulinemia, and severel...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Korean Association of Immunologists
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086452/ https://www.ncbi.nlm.nih.gov/pubmed/27799873 http://dx.doi.org/10.4110/in.2016.16.5.281 |