Mutagenic Effects of Ribavirin on Hepatitis E Virus—Viral Extinction versus Selection of Fitness-Enhancing Mutations

Hepatitis E virus (HEV), an important agent of viral hepatitis worldwide, can cause severe courses of infection in pregnant women and immunosuppressed patients. To date, HEV infections can only be treated with ribavirin (RBV). Major drawbacks of this therapy are that RBV is not approved for administ...

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Detalles Bibliográficos
Autores principales: Todt, Daniel, Walter, Stephanie, Brown, Richard J. P., Steinmann, Eike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086615/
https://www.ncbi.nlm.nih.gov/pubmed/27754363
http://dx.doi.org/10.3390/v8100283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086615/
https://www.ncbi.nlm.nih.gov/pubmed/27754363
http://dx.doi.org/10.3390/v8100283

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