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Establishment and Maintenance of the Human Naïve CD4(+) T-Cell Compartment
The naïve CD4(+) T-cell compartment is considered essential to guarantee immune competence throughout life. Its replenishment with naïve cells with broad diverse receptor repertoire, albeit with reduced self-reactivity, is ensured by the thymus. Nevertheless, cumulative data support a major requirem...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086629/ https://www.ncbi.nlm.nih.gov/pubmed/27843891 http://dx.doi.org/10.3389/fped.2016.00119 |