L-Asparaginase Isolated from Phaseolus vulgaris Seeds Exhibited Potent Anti-Acute Lymphoblastic Leukemia Effects In-Vitro and Low Immunogenic Properties In-Vivo

Escherichia coli-derived L-asparaginases have been used in the treatment of acute lymphoblastic leukemia (ALL), however, clinical hypersensitivity reactions and silent inactivation due to antibodies against E. coli-asparaginase, lead to inactivation of these preparations in most cases.Therefore, thi...

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Detalles Bibliográficos
Autores principales: Mohamed, Saleh A., Elshal, Mohamed F., Kumosani, Taha A., Aldahlawi, Alia M., Basbrain, Tasneem A., Alshehri, Fauziah A., Choudhry, Hani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086747/
https://www.ncbi.nlm.nih.gov/pubmed/27754445
http://dx.doi.org/10.3390/ijerph13101008

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