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Lhx2 Determines Odorant Receptor Expression Frequency in Mature Olfactory Sensory Neurons

A developmental program of epigenetic repression prepares each mammalian olfactory sensory neuron (OSN) to strongly express one allele from just one of hundreds of odorant receptor (OR) genes, but what completes this process of OR gene choice by driving the expression of this allele is incompletely...

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Detalles Bibliográficos
Autores principales: Zhang, Guangfan, Titlow, William B., Biecker, Stephanie M., Stromberg, Arnold J., McClintock, Timothy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086798/
https://www.ncbi.nlm.nih.gov/pubmed/27822500
http://dx.doi.org/10.1523/ENEURO.0230-16.2016