Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles

Palladium(II) acetate, in combination with triphenylphosphine, catalyzes direct arylation of 1,4-disubstituted 1,2,3-triazoles effectively. This C–H arylation reaction provides facile access to fully substituted triazoles with well-defined regiochemistry.

Detalles Bibliográficos
Autores principales: Zhang, Chengwei, You, Lin, Chen, Chuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086804/
https://www.ncbi.nlm.nih.gov/pubmed/27669198
http://dx.doi.org/10.3390/molecules21101268
_version_ 1782463807189155840
author Zhang, Chengwei
You, Lin
Chen, Chuo
author_facet Zhang, Chengwei
You, Lin
Chen, Chuo
author_sort Zhang, Chengwei
collection PubMed
description Palladium(II) acetate, in combination with triphenylphosphine, catalyzes direct arylation of 1,4-disubstituted 1,2,3-triazoles effectively. This C–H arylation reaction provides facile access to fully substituted triazoles with well-defined regiochemistry.
format Online
Article
Text
id pubmed-5086804
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-50868042016-10-31 Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles Zhang, Chengwei You, Lin Chen, Chuo Molecules Communication Palladium(II) acetate, in combination with triphenylphosphine, catalyzes direct arylation of 1,4-disubstituted 1,2,3-triazoles effectively. This C–H arylation reaction provides facile access to fully substituted triazoles with well-defined regiochemistry. MDPI 2016-09-22 /pmc/articles/PMC5086804/ /pubmed/27669198 http://dx.doi.org/10.3390/molecules21101268 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Zhang, Chengwei
You, Lin
Chen, Chuo
Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles
title Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles
title_full Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles
title_fullStr Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles
title_full_unstemmed Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles
title_short Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles
title_sort palladium-catalyzed c–h arylation of 1,2,3-triazoles
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086804/
https://www.ncbi.nlm.nih.gov/pubmed/27669198
http://dx.doi.org/10.3390/molecules21101268
work_keys_str_mv AT zhangchengwei palladiumcatalyzedcharylationof123triazoles
AT youlin palladiumcatalyzedcharylationof123triazoles
AT chenchuo palladiumcatalyzedcharylationof123triazoles

Ejemplares similares