Cargando…

Strontium inhibits titanium particle-induced osteoclast activation and chronic inflammation via suppression of NF-κB pathway

Wear-particle-induced chronic inflammation and osteoclastogenesis have been identified as critical factors of aseptic loosening. Although strontium is known to be involved in osteoclast differentiation, its effect on particle-induced inflammatory osteolysis remains unclear. In this study, we investi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Shijun, Hu, Xuanyang, Tao, Yunxia, Ping, Zichuan, Wang, Liangliang, Shi, Jiawei, Wu, Xiexing, Zhang, Wen, Yang, Huilin, Nie, Zhikui, Xu, Yaozeng, Wang, Zhirong, Geng, Dechun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087084/ https://www.ncbi.nlm.nih.gov/pubmed/27796351 http://dx.doi.org/10.1038/srep36251

Ejemplares similares

Lithium chloride inhibits titanium particle-induced osteoclastogenesis by inhibiting the NF-κB pathway
por: Hu, Xuanyang, et al.
Publicado: (2017)

Icariin attenuates titanium-particle inhibition of bone formation by activating the Wnt/β-catenin signaling pathway in vivo and in vitro
por: Wang, Junhua, et al.
Publicado: (2016)

Titanium particle-induced osteogenic inhibition and bone destruction are mediated by the GSK-3β/β-catenin signal pathway
por: Gu, Ye, et al.
Publicado: (2017)

Prolactin inhibits the progression of intervertebral disc degeneration through inactivation of the NF-κB pathway in rats
por: Wu, Xiexing, et al.
Publicado: (2018)

Urolithin B suppressed osteoclast activation and reduced bone loss of osteoporosis via inhibiting ERK/NF‐κB pathway
por: Li, Yajun, et al.
Publicado: (2022)

Identification of Key Genes and Potential Mechanisms Based on the Autophagy Regulatory Network in Osteoclasts Using a Murine Osteoarthritis Model
por: Zhang, Haifeng, et al.
Publicado: (2022)

Use of Polyphenol Tannic Acid to Functionalize Titanium with Strontium for Enhancement of Osteoblast Differentiation and Reduction of Osteoclast Activity
por: Steffi, Chris, et al.
Publicado: (2019)

Protective Effects of Punicalagin on Osteoporosis by Inhibiting Osteoclastogenesis and Inflammation via the NF-κB and MAPK Pathways
por: Wang, Wei, et al.
Publicado: (2020)

Puerarin inhibits titanium particle‐induced osteolysis and RANKL‐induced osteoclastogenesis via suppression of the NF‐κB signaling pathway
por: Tang, Wenkai, et al.
Publicado: (2020)

GSK-3β suppression upregulates Gli1 to alleviate osteogenesis inhibition in titanium nanoparticle-induced osteolysis
por: Wang, Qing, et al.
Publicado: (2022)

Harmine Alleviates Titanium Particle-Induced Inflammatory Bone Destruction by Immunomodulatory Effect on the Macrophage Polarization and Subsequent Osteogenic Differentiation
por: Wang, Liangliang, et al.
Publicado: (2021)

Strontium-doping promotes bone bonding of titanium implants in osteoporotic microenvironment
por: Geng, Tengyu, et al.
Publicado: (2022)

Puerarin alleviates osteoporosis in the ovariectomy-induced mice by suppressing osteoclastogenesis via inhibition of TRAF6/ROS-dependent MAPK/NF-κB signaling pathways
por: Xiao, Long, et al.
Publicado: (2020)

Paeoniflorin Ameliorates Hyperprolactinemia-Induced Inhibition of Osteoblastogenesis by Suppressing the NF-κB Signaling Pathway
por: Sun, Xiaohong, et al.
Publicado: (2022)

Chrysin Protects Against Titanium Particle-Induced Osteolysis by Attenuating Osteoclast Formation and Function by Inhibiting NF-κB and MAPK Signaling
por: Wu, Zuoxing, et al.
Publicado: (2022)

Nanomaterial-assisted theranosis of bone diseases
por: Zheng, Kai, et al.
Publicado: (2022)

Strontium Ranelate Inhibits Osteoclastogenesis through NF-κB-Pathway-Dependent Autophagy
por: Wu, Dongle, et al.
Publicado: (2023)

The Incorporation of Strontium in a Sodium Alginate Coating on Titanium Surfaces for Improved Biological Properties
por: Yuan, Ning, et al.
Publicado: (2017)

The Fabrication and Function of Strontium-modified Hierarchical Micro/Nano Titanium Implant
por: Wang, Haiyan, et al.
Publicado: (2020)

Immunomodulatory Effects of Calcium and Strontium Co-Doped Titanium Oxides on Osteogenesis
por: Yuan, Xiangwei, et al.
Publicado: (2017)

Reciprocal Role of ERK and Nf-κb Pathways in Survival and Activation of Osteoclasts
por: Miyazaki, Tsuyoshi, et al.
Publicado: (2000)

Nur77 Prevents Osteoporosis by Inhibiting the NF‐κB Signalling Pathway and Osteoclast Differentiation
por: Tian, Huanlian, et al.
Publicado: (2022)

Osteoblastic and anti-osteoclastic activities of strontium-substituted silicocarnotite ceramics: In vitro and in vivo studies
por: Zeng, Junkai, et al.
Publicado: (2020)

Engineering Stem Cell Recruitment and Osteoinduction via Bioadhesive Molecular Mimics to Improve Osteoporotic Bone-Implant Integration
por: Bai, Jiaxiang, et al.
Publicado: (2022)

Targeting strategies for bone diseases: signaling pathways and clinical studies
por: Xu, Hao, et al.
Publicado: (2023)

Comprehensive overview of microRNA function in rheumatoid arthritis
por: Peng, Xiaole, et al.
Publicado: (2023)

Inhibition of Sirtuin 3 prevents titanium particle-induced bone resorption and osteoclastsogenesis via suppressing ERK and JNK signaling
por: Li, Ning, et al.
Publicado: (2021)

Interleukin-17A upregulates receptor activator of NF-κB on osteoclast precursors
por: Adamopoulos, Iannis E, et al.
Publicado: (2010)

Inhibition of Osteoclast Differentiation by Carotenoid Derivatives through Inhibition of the NF-κB Pathway
por: Odes-Barth, Shlomit, et al.
Publicado: (2020)

Dehydromiltirone inhibits osteoclast differentiation in RAW264.7 and bone marrow macrophages by modulating MAPK and NF-κB activity
por: Deng, Wei, et al.
Publicado: (2022)

MiR‐106b inhibition suppresses inflammatory bone destruction of wear debris‐induced periprosthetic osteolysis in rats
por: Yu, Binqing, et al.
Publicado: (2020)

Strontium Peroxide-Loaded Composite Scaffolds Capable of Generating Oxygen and Modulating Behaviors of Osteoblasts and Osteoclasts
por: Lin, Sheng-Ju, et al.
Publicado: (2022)

Extracorporeal shock wave therapy inhibits osteoclast differentiation by targeting NF-κB signaling pathway
por: Chen, Bei, et al.
Publicado: (2023)

The effect of strontium ranelate on titanium particle-induced periprosthetic osteolysis regulated by WNT/β-catenin signaling in vivo and in vitro
por: Wang, Bolun, et al.
Publicado: (2021)

Effect of Bifidobacterium on osteoclasts: TNF-α/NF-κB inflammatory signal pathway-mediated mechanism
por: Wu, Yue, et al.
Publicado: (2023)

Entangled Titanium Fibre Balls Combined with Nano Strontium Hydroxyapatite in Repairing Bone Defects
por: Liu, Ping, et al.
Publicado: (2014)

NOX4 blockade suppresses titanium nanoparticle-induced bone destruction via activation of the Nrf2 signaling pathway
por: Wang, Wei, et al.
Publicado: (2022)

Strontium Ranelate Ameliorates Intervertebral Disc Degeneration via Regulating TGF-β1/NF-κB Axis
por: Sun, Ruping, et al.
Publicado: (2023)

Prednisolone induces osteoporosis-like phenotypes via focal adhesion signaling pathway in zebrafish larvae
por: Huo, Lei, et al.
Publicado: (2018)

CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts
por: Greenblatt, Matthew B., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_hhov9fm33duc7tb4u020ih97i0