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Lipid-based surface engineering of PLGA nanoparticles for drug and gene delivery applications
The use of poly(lactic-co-glycolic acid) (PLGA)-based nanocarriers presents several major challenges, including their synthetic hydrophobic surface, low transfection efficiency, short circulation half-life, and nonspecific tissue distribution. Numerous engineering strategies have been employed to ov...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087123/ https://www.ncbi.nlm.nih.gov/pubmed/27807476 http://dx.doi.org/10.1186/s40824-016-0081-3 |