Human blood myeloid and plasmacytoid dendritic cells cross activate each other and synergize in inducing NK cell cytotoxicity

Human blood dendritic cells (DCs) hold great potential for use in anticancer immunotherapies. CD1c(+) myeloid DCs and plasmacytoid DCs (pDCs) have been successfully utilized in clinical vaccination trials against melanoma. We hypothesize that combining both DC subsets in a single vaccine can further...

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Detalles Bibliográficos
Autores principales: van Beek, Jasper J. P., Gorris, Mark A. J., Sköld, Annette E., Hatipoglu, Ibrahim, Van Acker, Heleen H., Smits, Evelien L., de Vries, I. Jolanda M., Bakdash, Ghaith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087293/
https://www.ncbi.nlm.nih.gov/pubmed/27853652
http://dx.doi.org/10.1080/2162402X.2016.1227902

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