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A Mechatronic Loading Device to Stimulate Bone Growth via a Human Knee

This paper presents the design of an innovative device that applies dynamic mechanical load to human knee joints. Dynamic loading is employed by applying cyclic and periodic force on a target area. The repeated force loading was considered to be an effective modality for repair and rehabilitation of...

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Detalles Bibliográficos
Autores principales: Prabhala, Sai Krishna, Chien, Stanley, Yokota, Hiroki, Anwar, Sohel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087403/
https://www.ncbi.nlm.nih.gov/pubmed/27690057
http://dx.doi.org/10.3390/s16101615
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author Prabhala, Sai Krishna
Chien, Stanley
Yokota, Hiroki
Anwar, Sohel
author_facet Prabhala, Sai Krishna
Chien, Stanley
Yokota, Hiroki
Anwar, Sohel
author_sort Prabhala, Sai Krishna
collection PubMed
description This paper presents the design of an innovative device that applies dynamic mechanical load to human knee joints. Dynamic loading is employed by applying cyclic and periodic force on a target area. The repeated force loading was considered to be an effective modality for repair and rehabilitation of long bones that are subject to ailments like fractures, osteoporosis, osteoarthritis, etc. The proposed device design builds on the knowledge gained in previous animal and mechanical studies. It employs a modified slider-crank linkage mechanism actuated by a brushless Direct Current (DC) motor and provides uniform and cyclic force. The functionality of the device was simulated in a software environment and the structural integrity was analyzed using a finite element method for the prototype construction. The device is controlled by a microcontroller that is programmed to provide the desired loading force at a predetermined frequency and for a specific duration. The device was successfully tested in various experiments for its usability and full functionality. The results reveal that the device works according to the requirements of force magnitude and operational frequency. This device is considered ready to be used for a clinical study to examine whether controlled knee-loading could be an effective regimen for treating the stated bone-related ailments.
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spelling pubmed-50874032016-11-07 A Mechatronic Loading Device to Stimulate Bone Growth via a Human Knee Prabhala, Sai Krishna Chien, Stanley Yokota, Hiroki Anwar, Sohel Sensors (Basel) Article This paper presents the design of an innovative device that applies dynamic mechanical load to human knee joints. Dynamic loading is employed by applying cyclic and periodic force on a target area. The repeated force loading was considered to be an effective modality for repair and rehabilitation of long bones that are subject to ailments like fractures, osteoporosis, osteoarthritis, etc. The proposed device design builds on the knowledge gained in previous animal and mechanical studies. It employs a modified slider-crank linkage mechanism actuated by a brushless Direct Current (DC) motor and provides uniform and cyclic force. The functionality of the device was simulated in a software environment and the structural integrity was analyzed using a finite element method for the prototype construction. The device is controlled by a microcontroller that is programmed to provide the desired loading force at a predetermined frequency and for a specific duration. The device was successfully tested in various experiments for its usability and full functionality. The results reveal that the device works according to the requirements of force magnitude and operational frequency. This device is considered ready to be used for a clinical study to examine whether controlled knee-loading could be an effective regimen for treating the stated bone-related ailments. MDPI 2016-09-29 /pmc/articles/PMC5087403/ /pubmed/27690057 http://dx.doi.org/10.3390/s16101615 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Prabhala, Sai Krishna
Chien, Stanley
Yokota, Hiroki
Anwar, Sohel
A Mechatronic Loading Device to Stimulate Bone Growth via a Human Knee
title A Mechatronic Loading Device to Stimulate Bone Growth via a Human Knee
title_full A Mechatronic Loading Device to Stimulate Bone Growth via a Human Knee
title_fullStr A Mechatronic Loading Device to Stimulate Bone Growth via a Human Knee
title_full_unstemmed A Mechatronic Loading Device to Stimulate Bone Growth via a Human Knee
title_short A Mechatronic Loading Device to Stimulate Bone Growth via a Human Knee
title_sort mechatronic loading device to stimulate bone growth via a human knee
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087403/
https://www.ncbi.nlm.nih.gov/pubmed/27690057
http://dx.doi.org/10.3390/s16101615
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