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Visual and Plasmon Resonance Absorption Sensor for Adenosine Triphosphate Based on the High Affinity between Phosphate and Zr(IV)

Zr(IV) can form phosphate and Zr(IV) (–PO(3)(2−)–Zr(4+)–) complex owing to the high affinity between Zr(IV) with phosphate. Zr(IV) can induce the aggregation of gold nanoparticles (AuNPs), while adenosine triphosphate(ATP) can prevent Zr(IV)-induced aggregation of AuNPs. Herein, a visual and plasmon...

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Detalles Bibliográficos
Autores principales: Qi, Wenjing, Liu, Zhongyuan, Zhang, Wei, Halawa, Mohamed Ibrahim, Xu, Guobao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087462/
https://www.ncbi.nlm.nih.gov/pubmed/27754349
http://dx.doi.org/10.3390/s16101674
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author Qi, Wenjing
Liu, Zhongyuan
Zhang, Wei
Halawa, Mohamed Ibrahim
Xu, Guobao
author_facet Qi, Wenjing
Liu, Zhongyuan
Zhang, Wei
Halawa, Mohamed Ibrahim
Xu, Guobao
author_sort Qi, Wenjing
collection PubMed
description Zr(IV) can form phosphate and Zr(IV) (–PO(3)(2−)–Zr(4+)–) complex owing to the high affinity between Zr(IV) with phosphate. Zr(IV) can induce the aggregation of gold nanoparticles (AuNPs), while adenosine triphosphate(ATP) can prevent Zr(IV)-induced aggregation of AuNPs. Herein, a visual and plasmon resonance absorption (PRA)sensor for ATP have been developed using AuNPs based on the high affinity between Zr(IV)with ATP. AuNPs get aggregated in the presence of certain concentrations of Zr(IV). After the addition of ATP, ATP reacts with Zr(IV) and prevents AuNPs from aggregation, enabling the detection of ATP. Because of the fast interaction of ATP with Zr(IV), ATP can be detected with a detection limit of 0.5 μM within 2 min by the naked eye. Moreover, ATP can be detected by the PRA technique with higher sensitivity. The A(520nm)/A(650nm) values in PRA spectra increase linearly with the concentrations of ATP from 0.1 μM to 15 μM (r = 0.9945) with a detection limit of 28 nM. The proposed visual and PRA sensor exhibit good selectivity against adenosine, adenosine monophosphate, guanosine triphosphate, cytidine triphosphate and uridine triphosphate. The recoveries for the analysis of ATP in synthetic samples range from 95.3% to 102.0%. Therefore, the proposed novel sensor for ATP is promising for real-time or on-site detection of ATP.
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spelling pubmed-50874622016-11-07 Visual and Plasmon Resonance Absorption Sensor for Adenosine Triphosphate Based on the High Affinity between Phosphate and Zr(IV) Qi, Wenjing Liu, Zhongyuan Zhang, Wei Halawa, Mohamed Ibrahim Xu, Guobao Sensors (Basel) Article Zr(IV) can form phosphate and Zr(IV) (–PO(3)(2−)–Zr(4+)–) complex owing to the high affinity between Zr(IV) with phosphate. Zr(IV) can induce the aggregation of gold nanoparticles (AuNPs), while adenosine triphosphate(ATP) can prevent Zr(IV)-induced aggregation of AuNPs. Herein, a visual and plasmon resonance absorption (PRA)sensor for ATP have been developed using AuNPs based on the high affinity between Zr(IV)with ATP. AuNPs get aggregated in the presence of certain concentrations of Zr(IV). After the addition of ATP, ATP reacts with Zr(IV) and prevents AuNPs from aggregation, enabling the detection of ATP. Because of the fast interaction of ATP with Zr(IV), ATP can be detected with a detection limit of 0.5 μM within 2 min by the naked eye. Moreover, ATP can be detected by the PRA technique with higher sensitivity. The A(520nm)/A(650nm) values in PRA spectra increase linearly with the concentrations of ATP from 0.1 μM to 15 μM (r = 0.9945) with a detection limit of 28 nM. The proposed visual and PRA sensor exhibit good selectivity against adenosine, adenosine monophosphate, guanosine triphosphate, cytidine triphosphate and uridine triphosphate. The recoveries for the analysis of ATP in synthetic samples range from 95.3% to 102.0%. Therefore, the proposed novel sensor for ATP is promising for real-time or on-site detection of ATP. MDPI 2016-10-12 /pmc/articles/PMC5087462/ /pubmed/27754349 http://dx.doi.org/10.3390/s16101674 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Qi, Wenjing
Liu, Zhongyuan
Zhang, Wei
Halawa, Mohamed Ibrahim
Xu, Guobao
Visual and Plasmon Resonance Absorption Sensor for Adenosine Triphosphate Based on the High Affinity between Phosphate and Zr(IV)
title Visual and Plasmon Resonance Absorption Sensor for Adenosine Triphosphate Based on the High Affinity between Phosphate and Zr(IV)
title_full Visual and Plasmon Resonance Absorption Sensor for Adenosine Triphosphate Based on the High Affinity between Phosphate and Zr(IV)
title_fullStr Visual and Plasmon Resonance Absorption Sensor for Adenosine Triphosphate Based on the High Affinity between Phosphate and Zr(IV)
title_full_unstemmed Visual and Plasmon Resonance Absorption Sensor for Adenosine Triphosphate Based on the High Affinity between Phosphate and Zr(IV)
title_short Visual and Plasmon Resonance Absorption Sensor for Adenosine Triphosphate Based on the High Affinity between Phosphate and Zr(IV)
title_sort visual and plasmon resonance absorption sensor for adenosine triphosphate based on the high affinity between phosphate and zr(iv)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087462/
https://www.ncbi.nlm.nih.gov/pubmed/27754349
http://dx.doi.org/10.3390/s16101674
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