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Responsive Boronic Acid-Decorated (Co)polymers: From Glucose Sensors to Autonomous Drug Delivery

Boronic acid-containing (co)polymers have fascinated researchers for decades, garnering attention for their unique responsiveness toward 1,2- and 1,3-diols, including saccharides and nucleotides. The applications of materials that exert this property are manifold including sensing, but also self-reg...

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Detalles Bibliográficos
Autores principales: Vancoillie, Gertjan, Hoogenboom, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087521/
https://www.ncbi.nlm.nih.gov/pubmed/27775572
http://dx.doi.org/10.3390/s16101736
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author Vancoillie, Gertjan
Hoogenboom, Richard
author_facet Vancoillie, Gertjan
Hoogenboom, Richard
author_sort Vancoillie, Gertjan
collection PubMed
description Boronic acid-containing (co)polymers have fascinated researchers for decades, garnering attention for their unique responsiveness toward 1,2- and 1,3-diols, including saccharides and nucleotides. The applications of materials that exert this property are manifold including sensing, but also self-regulated drug delivery systems through responsive membranes or micelles. In this review, some of the main applications of boronic acid containing (co)polymers are discussed focusing on the role of the boronic acid group in the response mechanism. We hope that this summary, which highlights the importance and potential of boronic acid-decorated polymeric materials, will inspire further research within this interesting field of responsive polymers and polymeric materials.
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spelling pubmed-50875212016-11-07 Responsive Boronic Acid-Decorated (Co)polymers: From Glucose Sensors to Autonomous Drug Delivery Vancoillie, Gertjan Hoogenboom, Richard Sensors (Basel) Review Boronic acid-containing (co)polymers have fascinated researchers for decades, garnering attention for their unique responsiveness toward 1,2- and 1,3-diols, including saccharides and nucleotides. The applications of materials that exert this property are manifold including sensing, but also self-regulated drug delivery systems through responsive membranes or micelles. In this review, some of the main applications of boronic acid containing (co)polymers are discussed focusing on the role of the boronic acid group in the response mechanism. We hope that this summary, which highlights the importance and potential of boronic acid-decorated polymeric materials, will inspire further research within this interesting field of responsive polymers and polymeric materials. MDPI 2016-10-19 /pmc/articles/PMC5087521/ /pubmed/27775572 http://dx.doi.org/10.3390/s16101736 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Vancoillie, Gertjan
Hoogenboom, Richard
Responsive Boronic Acid-Decorated (Co)polymers: From Glucose Sensors to Autonomous Drug Delivery
title Responsive Boronic Acid-Decorated (Co)polymers: From Glucose Sensors to Autonomous Drug Delivery
title_full Responsive Boronic Acid-Decorated (Co)polymers: From Glucose Sensors to Autonomous Drug Delivery
title_fullStr Responsive Boronic Acid-Decorated (Co)polymers: From Glucose Sensors to Autonomous Drug Delivery
title_full_unstemmed Responsive Boronic Acid-Decorated (Co)polymers: From Glucose Sensors to Autonomous Drug Delivery
title_short Responsive Boronic Acid-Decorated (Co)polymers: From Glucose Sensors to Autonomous Drug Delivery
title_sort responsive boronic acid-decorated (co)polymers: from glucose sensors to autonomous drug delivery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087521/
https://www.ncbi.nlm.nih.gov/pubmed/27775572
http://dx.doi.org/10.3390/s16101736
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