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Optimizing Porcine Islet Isolation to Markedly Reduce Enzyme Consumption Without Sacrificing Islet Yield or Function

BACKGROUND: Human allogeneic islet transplantation for treatment of type 1 diabetes provides numerous clinical benefits, such as fewer episodes of hypoglycemic unawareness and tighter control of blood glucose levels. Availability of human pancreas for clinical and research use, however, is severely...

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Detalles Bibliográficos
Autores principales: Holdcraft, Robert W., Green, Michael L., Breite, Andrew G., Circle, Lisa, Meyer, Eric D., Adkins, Hollie, Harbeck, Steven G., Smith, Barry H., Gazda, Lawrence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087567/
https://www.ncbi.nlm.nih.gov/pubmed/27830180
http://dx.doi.org/10.1097/TXD.0000000000000599

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