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Inhibition of Shh signalling in the chick wing gives insights into digit patterning and evolution

In an influential model of pattern formation, a gradient of Sonic hedgehog (Shh) signalling in the chick wing bud specifies cells with three antero-posterior positional values, which give rise to three morphologically different digits by a self-organizing mechanism with Turing-like properties. Howev...

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Detalles Bibliográficos
Autores principales: Pickering, Joseph, Towers, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087615/
https://www.ncbi.nlm.nih.gov/pubmed/27702785
http://dx.doi.org/10.1242/dev.137398