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LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes
Autophagy is an evolutionarily conserved process used for removing surplus and damaged proteins and organelles from the cytoplasm. The unwanted material is incorporated into autophagosomes that eventually fuse with lysosomes, leading to the degradation of their cargo. The fusion event is mediated by...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087675/ https://www.ncbi.nlm.nih.gov/pubmed/27628032 http://dx.doi.org/10.1242/bio.018648 |