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Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C

The spindle assembly checkpoint (SAC) inhibits the anaphase-promoting complex/cyclosome (APC/C) in response to unattached kinetochores by generating a diffusible inhibitor termed the mitotic checkpoint complex (MCC). At metaphase, rapid activation of the APC/C requires removal of the MCC, a process...

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Detalles Bibliográficos
Autores principales:	Garvanska, Dimitriya H., Larsen, Marie Sofie Yoo, Nilsson, Jakob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087681/ https://www.ncbi.nlm.nih.gov/pubmed/27591192 http://dx.doi.org/10.1242/bio.020842

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