The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma

The cell's repertoire of transfer RNAs (tRNAs) has been linked to cancer. Recently, the level of the initiator methionine tRNA (tRNA(i)(Met)) in stromal fibroblasts has been shown to influence extracellular matrix (ECM) secretion to drive tumour growth and angiogenesis. Here we show that increa...

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Detalles Bibliográficos
Autores principales: Birch, Joanna, Clarke, Cassie J., Campbell, Andrew D., Campbell, Kirsteen, Mitchell, Louise, Liko, Dritan, Kalna, Gabriela, Strathdee, Douglas, Sansom, Owen J., Neilson, Matthew, Blyth, Karen, Norman, Jim C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087684/
https://www.ncbi.nlm.nih.gov/pubmed/27543055
http://dx.doi.org/10.1242/bio.019075

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