Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation

Centrosomes are major microtubule-organizing centers composed of centrioles surrounded by an extensive proteinacious layer called the pericentriolar material (PCM). In Caenorhabditis elegans embryos, the mitotic PCM expands by Polo-like kinase 1 (PLK-1) phosphorylation-accelerated assembly of SPD-5...

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Detalles Bibliográficos
Autores principales: Wueseke, Oliver, Zwicker, David, Schwager, Anne, Wong, Yao Liang, Oegema, Karen, Jülicher, Frank, Hyman, Anthony A., Woodruff, Jeffrey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087692/
https://www.ncbi.nlm.nih.gov/pubmed/27591191
http://dx.doi.org/10.1242/bio.020990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087692/
https://www.ncbi.nlm.nih.gov/pubmed/27591191
http://dx.doi.org/10.1242/bio.020990

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