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Improvement of intratumor microdistribution of PEGylated liposome via tumor priming by metronomic S-1 dosing
The efficient delivery of nanocarrier-based cancer therapeutics into tumor tissue is problematic. Structural abnormalities, tumor vasculature heterogeneity, and elevated intratumor pressure impose barriers against the preferential accumulation of nanocarrier-based cancer therapeutics within tumor ti...
Autores principales: | Doi, Yusuke, Abu Lila, Amr S, Matsumoto, Haruna, Okada, Tomoko, Shimizu, Taro, Ishida, Tatsuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087787/ https://www.ncbi.nlm.nih.gov/pubmed/27822036 http://dx.doi.org/10.2147/IJN.S119069 |
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