Cargando…

The accumulation of macrophages attenuates the effect of recombinant human endostatin on lung cancer

BACKGROUND: Although anti-angiogenic therapy is widely applied clinically, its efficacy has been less than expected. Screening for regulatory factors and sensitive indicators to define the effectiveness of these drugs is required. Through a retrospective study of clinical data, we found that patient...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yanyang, Tu, Li, Wang, Li, Long, Jianlin, Wang, Jiantao, Wang, Yuyi, Luo, Feng, Cao, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087788/ https://www.ncbi.nlm.nih.gov/pubmed/27822063 http://dx.doi.org/10.2147/OTT.S114389

Ejemplares similares

Hypoxia and TGF-β1 lead to endostatin resistance by cooperatively increasing cancer stem cells in A549 transplantation tumors
por: Wang, Yuyi, et al.
Publicado: (2015)

Antiangiogenic effects of recombinant human endostatin in lung cancers
por: He, Lang, et al.
Publicado: (2018)

Recombinant human endostatin combined with chemotherapy for advanced squamous cell lung cancer: a meta-analysis
por: Feng, Li, et al.
Publicado: (2021)

Insights on CXC chemokine receptor 2 in breast cancer: An emerging target for oncotherapy
por: Guo, Fengzhu, et al.
Publicado: (2019)

CXCR2 is a novel cancer stem-like cell marker for triple-negative breast cancer
por: Wang, Yuyi, et al.
Publicado: (2018)

Comparisons of biophysical properties and bioactivities of mono-PEGylated endostatin and an endostatin analog
por: Wang, Shan, et al.
Publicado: (2016)

Clinical effects of cisplatin plus recombinant human endostatin (rh-endostatin) intratumoral injection on malignant central airway obstruction: a retrospective analysis of 319 cases
por: Zhou, Yunzhi, et al.
Publicado: (2021)

Recombinant human endostatin in combination with CHOP regimen for peripheral T cell lymphoma
por: Zhang, Qunling, et al.
Publicado: (2016)

Recombinant human endostatin combined with radiotherapy inhibits colorectal cancer growth
por: Zhang, Ke, et al.
Publicado: (2017)

Current Status and Study Progress of Recombinant Human Endostatin in Cancer Treatment
por: Li, Kai, et al.
Publicado: (2018)

Decitabine reverses TGF-β1-induced epithelial–mesenchymal transition in non-small-cell lung cancer by regulating miR-200/ZEB axis
por: Zhang, Nan, et al.
Publicado: (2017)

Safety and efficacy of nivolumab plus recombinant human endostatin in previously treated advanced non-small-cell lung cancer
por: Lv, Weize, et al.
Publicado: (2022)

Systematic Evaluation Meta-Analysis of the Efficacy of Recombinant Human Endostatin Combined with Gemcitabine and Cisplatin in Non-Small-Cell Lung Cancer
por: Zhang, Li, et al.
Publicado: (2022)

Recombinant Endostatin as a Potential Radiosensitizer in the Treatment of Non-Small Cell Lung Cancer
por: Cunningham, Charnay, et al.
Publicado: (2023)

Zoledronic acid inhibits the growth of cancer stem cell derived from cervical cancer cell by attenuating their stemness phenotype and inducing apoptosis and cell cycle arrest through the Erk1/2 and Akt pathways
por: Wang, Li, et al.
Publicado: (2019)

Recombinant Human Endostatin Endostar Suppresses Angiogenesis and Lymphangiogenesis of Malignant Pleural Effusion in Mice
por: Ma, Xingqun, et al.
Publicado: (2012)

Combined BRM270 and endostatin inhibit relapse of NSCLC while suppressing lung cancer stem cell proliferation induced by endostatin
por: Gu, Yan-hui, et al.
Publicado: (2021)

Differential effects of recombinant human endostatin treatment on differentiated and undifferentiated blood vessels in Lewis lung cancer
por: Fu, Weijiang, et al.
Publicado: (2017)

Continuous intravenous infusion of recombinant human endostatin using infusion pump plus chemotherapy in non-small cell lung cancer
por: Qin, Zhi-Quan, et al.
Publicado: (2022)

Utilization of lung cancer cell lines for the study of lung cancer stem cells
por: Wang, Yuyi, et al.
Publicado: (2018)

Recombinant Human Endostatin Normalizes Tumor Vasculature and Enhances Radiation Response in Xenografted Human Nasopharyngeal Carcinoma Models
por: Peng, Fang, et al.
Publicado: (2012)

Recombined humanized endostatin (Endostar) intravenous infusion in the treatment of refractory nasopharyngeal carcinoma: Three case reports
por: Chen, Chen, et al.
Publicado: (2019)

Recombined humanized endostatin (Endostar) combined with chemotherapy for advanced bone and soft tissue sarcomas in stage IV
por: Xing, Peipei, et al.
Publicado: (2016)

Endostatin in the pancreas
por: Wigmore, S J
Publicado: (2005)

Recombined humanized endostatin‐induced suppression of HMGB1 expression inhibits proliferation of NSCLC cancer cells
por: Meng, Fan‐Jie, et al.
Publicado: (2018)

Combining therapy with recombinant human endostatin and cytotoxic agents for recurrent disseminated glioblastoma: a retrospective study
por: Ge, Jing-jing, et al.
Publicado: (2020)

E-M, an Engineered Endostatin with High ATPase Activity, Inhibits the Recruitment and Alternative Activation of Macrophages in Non-small Cell Lung Cancer
por: Xu, Min, et al.
Publicado: (2017)

Antiangiogenic therapy using endostatin increases the number of ALDH+ lung cancer stem cells by generating intratumor hypoxia
por: Yu, Yang, et al.
Publicado: (2016)

Real‐world outcomes of various regimens of recombinant human endostatin combined with chemotherapy in non‐driver gene mutation advanced non‐small cell lung cancer
por: Wang, Zhongtai, et al.
Publicado: (2019)

Recombinant Human Endostatin Endostar Inhibits Tumor Growth and Metastasis in a Mouse Xenograft Model of Colon Cancer
por: Jia, Yitao, et al.
Publicado: (2011)

Clinical evaluation of vascular normalization induced by recombinant human endostatin in nasopharyngeal carcinoma via dynamic contrast-enhanced ultrasonography
por: Yang, Zhendong, et al.
Publicado: (2018)

Enhancement of Recombinant Human Endostatin on the Radiosensitivity of Human Pulmonary Adenocarcinoma A549 Cells and Its Mechanism
por: Jiang, Xiao-dong, et al.
Publicado: (2012)

Case Report: Recombinant Human Endostatin Plus Chemotherapy for Epidermal Growth Factor Receptor-Negative Miliary Lung Adenocarcinoma
por: Zhu, Jian, et al.
Publicado: (2022)

Recombinant Human Endostatin Suppresses Mouse Osteoclast Formation by Inhibiting the NF-κB and MAPKs Signaling Pathways
por: Chen, Nong, et al.
Publicado: (2016)

The Construction of a Radiation-Induced Brain Injury Model and Preliminary Study on the Effect of Human Recombinant Endostatin in Treating Radiation-Induced Brain Injury
por: Ma, Chenying, et al.
Publicado: (2019)

Antitumor activities of Liver-targeting peptide modified Recombinant human Endostatin in BALB/c-nu mice with Hepatocellular carcinoma
por: Yan, Ma, et al.
Publicado: (2017)

Autoantibodies to endostatin in patients with breast cancer: correlation to endostatin levels and clinical outcome
por: Bachelot, T, et al.
Publicado: (2006)

Endostar, a Modified Recombinant Human Endostatin, Suppresses Angiogenesis through Inhibition of Wnt/β-Catenin Signaling Pathway
por: Xu, Xiaoming, et al.
Publicado: (2014)

Gold Nanoparticle–Mediated Targeted Delivery of Recombinant Human Endostatin Normalizes Tumour Vasculature and Improves Cancer Therapy
por: Li, Wei, et al.
Publicado: (2016)

Gene therapy of renal cancer using recombinant adeno-associated virus encoding human endostatin
por: Sun, Erlin, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_g2hlvkt41ujmfftho37386gk1u