Cargando…
Clinicopathological characteristics, treatment, and survival outcomes of cystadenocarcinoma of the salivary gland: a population-based study
BACKGROUND: The aim of this study was to investigate the clinicopathological characteristics, treatment, and survival of cystadenocarcinoma of the salivary gland. PATIENTS AND METHODS: Cases in the Surveillance, Epidemiology, and End Results database from 1991 to 2012 were identified. Factors signif...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087798/ https://www.ncbi.nlm.nih.gov/pubmed/27822061 http://dx.doi.org/10.2147/OTT.S111247 |
_version_ | 1782463974240944128 |
---|---|
author | Cai, Cheng-Fu Sun, Jia-Yuan He, Zhen-Yu Lin, Huan-Xin Liu, Fa-Rong Wang, Yan |
author_facet | Cai, Cheng-Fu Sun, Jia-Yuan He, Zhen-Yu Lin, Huan-Xin Liu, Fa-Rong Wang, Yan |
author_sort | Cai, Cheng-Fu |
collection | PubMed |
description | BACKGROUND: The aim of this study was to investigate the clinicopathological characteristics, treatment, and survival of cystadenocarcinoma of the salivary gland. PATIENTS AND METHODS: Cases in the Surveillance, Epidemiology, and End Results database from 1991 to 2012 were identified. Factors significantly associated with survival were identified using Kaplan–Meier survival analysis and Cox proportional hazard regression. RESULTS: A total of 65 patients were identified; of these patients, 64 received surgical treatment, 25 underwent lymphadenectomy, and four (16.0%) patients had nodal metastasis and only one (2.1%) patient had poorly differentiated disease. The most common tumor location was the parotid gland (87.7%). The median follow-up was 55 months. None of the patients died of salivary gland malignant-tumor-related disease. The 5- and 10-year cause-specific survival rates were 97.0% and 81.4%, respectively. The 5- and 10-year overall survival rates were 84.6% and 60.7%, respectively. Surgical procedures, lymphadenectomy, and adjuvant radiotherapy did not affect survival. CONCLUSION: Salivary gland cystadenocarcinoma is extremely rare but has an excellent prognosis, and surgery is the mainstay of treatment. |
format | Online Article Text |
id | pubmed-5087798 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-50877982016-11-07 Clinicopathological characteristics, treatment, and survival outcomes of cystadenocarcinoma of the salivary gland: a population-based study Cai, Cheng-Fu Sun, Jia-Yuan He, Zhen-Yu Lin, Huan-Xin Liu, Fa-Rong Wang, Yan Onco Targets Ther Original Research BACKGROUND: The aim of this study was to investigate the clinicopathological characteristics, treatment, and survival of cystadenocarcinoma of the salivary gland. PATIENTS AND METHODS: Cases in the Surveillance, Epidemiology, and End Results database from 1991 to 2012 were identified. Factors significantly associated with survival were identified using Kaplan–Meier survival analysis and Cox proportional hazard regression. RESULTS: A total of 65 patients were identified; of these patients, 64 received surgical treatment, 25 underwent lymphadenectomy, and four (16.0%) patients had nodal metastasis and only one (2.1%) patient had poorly differentiated disease. The most common tumor location was the parotid gland (87.7%). The median follow-up was 55 months. None of the patients died of salivary gland malignant-tumor-related disease. The 5- and 10-year cause-specific survival rates were 97.0% and 81.4%, respectively. The 5- and 10-year overall survival rates were 84.6% and 60.7%, respectively. Surgical procedures, lymphadenectomy, and adjuvant radiotherapy did not affect survival. CONCLUSION: Salivary gland cystadenocarcinoma is extremely rare but has an excellent prognosis, and surgery is the mainstay of treatment. Dove Medical Press 2016-10-25 /pmc/articles/PMC5087798/ /pubmed/27822061 http://dx.doi.org/10.2147/OTT.S111247 Text en © 2016 Cai et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Cai, Cheng-Fu Sun, Jia-Yuan He, Zhen-Yu Lin, Huan-Xin Liu, Fa-Rong Wang, Yan Clinicopathological characteristics, treatment, and survival outcomes of cystadenocarcinoma of the salivary gland: a population-based study |
title | Clinicopathological characteristics, treatment, and survival outcomes of cystadenocarcinoma of the salivary gland: a population-based study |
title_full | Clinicopathological characteristics, treatment, and survival outcomes of cystadenocarcinoma of the salivary gland: a population-based study |
title_fullStr | Clinicopathological characteristics, treatment, and survival outcomes of cystadenocarcinoma of the salivary gland: a population-based study |
title_full_unstemmed | Clinicopathological characteristics, treatment, and survival outcomes of cystadenocarcinoma of the salivary gland: a population-based study |
title_short | Clinicopathological characteristics, treatment, and survival outcomes of cystadenocarcinoma of the salivary gland: a population-based study |
title_sort | clinicopathological characteristics, treatment, and survival outcomes of cystadenocarcinoma of the salivary gland: a population-based study |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087798/ https://www.ncbi.nlm.nih.gov/pubmed/27822061 http://dx.doi.org/10.2147/OTT.S111247 |
work_keys_str_mv | AT caichengfu clinicopathologicalcharacteristicstreatmentandsurvivaloutcomesofcystadenocarcinomaofthesalivaryglandapopulationbasedstudy AT sunjiayuan clinicopathologicalcharacteristicstreatmentandsurvivaloutcomesofcystadenocarcinomaofthesalivaryglandapopulationbasedstudy AT hezhenyu clinicopathologicalcharacteristicstreatmentandsurvivaloutcomesofcystadenocarcinomaofthesalivaryglandapopulationbasedstudy AT linhuanxin clinicopathologicalcharacteristicstreatmentandsurvivaloutcomesofcystadenocarcinomaofthesalivaryglandapopulationbasedstudy AT liufarong clinicopathologicalcharacteristicstreatmentandsurvivaloutcomesofcystadenocarcinomaofthesalivaryglandapopulationbasedstudy AT wangyan clinicopathologicalcharacteristicstreatmentandsurvivaloutcomesofcystadenocarcinomaofthesalivaryglandapopulationbasedstudy |