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Self-assembling peptide nanofibers containing phenylalanine for the controlled release of 5-fluorouracil
The study shows that RADA-F6 peptide with pH-responsive self-assembling nature can be effectively used as a drug delivery system for the sustained release of a potent anticancer drug 5-fluorouracil (5-FU) at basic pH. As 5-FU contains the aromatic pyrimidine ring, RADA-F6 system is suitable for entr...
Autores principales: | Ashwanikumar, Narayanan, Kumar, Nisha Asok, Saneesh Babu, Padma S, Sivakumar, Krishnankutty C, Vadakkan, Mithun Varghese, Nair, Parvathi, Hema Saranya, Ilamathi, Asha Nair, Sivakumari, Vinod Kumar, Gopalakrishnapillai S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087806/ https://www.ncbi.nlm.nih.gov/pubmed/27822037 http://dx.doi.org/10.2147/IJN.S104707 |
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